Sitagliptin Phosphate Hydrate

Fine Chemicals Sitagliptin Phosphate Hydrate(CAS: *-77-9)Chemical informationProduct Name: Sitagliptin Phosphate HydrateSynonym: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate;Sitagliptin phosphate monohydrate;Sitagliptin phosphate for research;D*;Januvia (tn);Sitagliptin phosphate (usan);Sitagliptin phosphate hydrate;Sitagliptin phosphate hydrate (jan)Appearance: white crystallineCAS No.: *-77-9Molecular Formula: C16H20F6N5O6PMolecular Weight: 523.*Purity: 99%+Packing: Foil Bag or as Required    Product Description:Sitagliptin phosphate monohydrate is a white to off-white, crystalline, non-hygroscopic powder. It is soluble in water and N,N-dimethyl formamide; slightly soluble in methanol; very slightly soluble in ethanol, acetone, and acetonitrile; and insoluble in isopropanol and isopropyl acetate.An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.What it is used for:Sitagliptin phosphate monohydrate is used to lower blood sugar levels in patients with type 2 diabetes mellitus alone or in combination with certain other medicines (metformin, medicines such as rosiglitazone and pioglitazone, a sulfonylurea medicine such as glimepiride, gliclazide and glibenclamide), when diet plus exercise or the other medicine(s) do not provide adequate blood sugar level control.COA:TestsSpecifications ResultsCharactersWhite to off-white crystalline powderCompliesIdentificationIR:similar to Reference StandardCompliesAppearance of solutionClear and colorlessCompliesLoss on Drying≤0.5%0.06%Sulphated Ash≤0.2%0.03%Heavy metals
Sitagliptin Phosphate Hydrate